Ultrasound-powered nanomotors to deliver Cas9

CRISPR-Cas9 has been a revolution in genome editing, from bacteria to humans. However, the efficiency delivering Cas9 and the sgRNA is one of the limiting points in the process. Researchers used plasmid-base delivery systems, nano-vesicles or nano-particles to improve the efficiency delivering the CRISPR systems. In this new article, “Active Intracellular Delivery of a Cas9/sgRNA Complex … Read more

NIH ensure $190M for CRISPR Genome Editing Research

The NIH plans to invest $190M during the next 6 years to fund researchers developing tools and technologies to ensure safety and effectiveness in genome editing in humans, focus on non-reproductive somatic cells. NIH Director Dr. Francis S. Collins declare yesterday that “Genome editing technologies such as CRISPR/Cas9 are revolutionizing biomedical research. The focus of the … Read more

CRISPR Journal debuts

(The picture corresponds to the @CRISPRlab at North Carolina State University where Rodolphe Barrangou works as a Professor). Before the end of 2017 we published the announcement of a new scientific journal exclusively based on CRISPR, The CRISPR Journal which belongs to Mary Ann Liebert, Inc Publishers. This week the first edition online came out: “The … Read more

CRISPR-editing in cacao plants

Cacao is an important food crop used widely around the world by 50 million people. However this wonderful plan that allow to make our sweet dreams possible, like chocolate, suffer a numerous of plant diseases. The Innovative Genomic Institute (IGI) an academic research partnership between UC Berkeley and UC San Francisco aims to develop DNA … Read more

First Human Embryos edited in USA

Shoukhrat Mitalipov of Oregon Health and Science University, in Portland, has lead the team that carried out the first attempt to genetically modify human embryos with CRISPR. The aim of this project was to demonstrate that it is possible to safely and efficiently correct defective genes that cause inherited diseases in humans. Indeed, this is gene … Read more